Polynucleotide Treatment at Dr Nyla Medispa

Led by Dr Nyla Raja, MBChB (Hons), MRCGP (Dist), DFFP, DPDermatology (GMC No. 6057913)

  • Award-winning clinics in London, Cheshire, and Liverpool
  • Doctor-led polynucleotide treatments by medical professionals
  • Supports skin regeneration for firmer, healthier-looking skin

Polynucleotides are a non-surgical bio-regenerative injectable treatment designed to improve skin quality, hydration, firmness, and overall skin health. Unlike dermal fillers, polynucleotides do not add volume. Instead, they stimulate fibroblast activity and support the body’s natural collagen and elastin production, helping to improve concerns such as fine lines, tired-looking eyes, loose skin, and uneven skin texture.

With clinics in London, Cheshire, and Liverpool, polynucleotide treatments are performed within a medically regulated setting under the guidance of Dr Nyla Raja and her experienced medical team. Treatment plans are tailored to individual concerns, with a focus on long-term skin rejuvenation and natural-looking improvement.

Prices start from £250 – book your free consultation to discuss whether polynucleotide treatment is suitable for you.

 
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Results

Improved hydration and skin firmness

Downtime

Minimal

Longevity

Up to 12–18 months

Treatment Time

30 minutes

Before & After Polynucleotide Treatment

Refined, natural-looking results tailored to each patient

Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Mayfair, London
Before
Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Mayfair, London
After
Before and after polynucleotide treatment for ageing skin concerns at Dr Nyla Medispa in Alderley Edge, Cheshire
Before
Before and after polynucleotide treatment for ageing skin concerns at Dr Nyla Medispa in Alderley Edge, Cheshire
After
Before and after polynucleotide treatment for facial skin rejuvenation in a male patient at Dr Nyla Medispa in Crosby, Liverpool
Before
Before and after polynucleotide treatment for facial skin rejuvenation in a male patient at Dr Nyla Medispa in Crosby, Liverpool
After
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
Before
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
After
Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Alderley Edge, Cheshire
Before
Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Alderley Edge, Cheshire
After
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
Before
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
After
Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Mayfair, London
Before
Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Mayfair, London
After
Before and after polynucleotide treatment for ageing skin concerns at Dr Nyla Medispa in Alderley Edge, Cheshire
Before
Before and after polynucleotide treatment for ageing skin concerns at Dr Nyla Medispa in Alderley Edge, Cheshire
After
Before and after polynucleotide treatment for facial skin rejuvenation in a male patient at Dr Nyla Medispa in Crosby, Liverpool
Before
Before and after polynucleotide treatment for facial skin rejuvenation in a male patient at Dr Nyla Medispa in Crosby, Liverpool
After
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
Before
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
After
Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Alderley Edge, Cheshire
Before
Before and after polynucleotide treatment for facial skin rejuvenation at Dr Nyla Medispa in Alderley Edge, Cheshire
After
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
Before
Before and after polynucleotide treatment for under-eye rejuvenation at Dr Nyla Medispa in Mayfair, London
After

*Disclaimer: Results and patient experience may vary. These are dependent on a number of factors such as age, medical history and lifestyle.

Patient undergoing polynucleotide treatment for skin rejuvenation at Dr Nyla Medispa in Mayfair, London
Patient undergoing polynucleotide treatment for skin rejuvenation at Dr Nyla Medispa in Alderley Edge, Cheshire
Women’s health consultation at Dr Nyla Medispa in Alderley Edge, Cheshire

Polynucleotide Treatment FAQs

What are polynucleotide treatments and how do they work?

Polynucleotides are advanced bio-regenerative injectables designed to improve skin quality, firmness, hydration, and elasticity. Unlike dermal fillers, polynucleotides do not restore volume or alter facial contours. Instead, they work by supporting the skin’s natural repair processes and stimulating fibroblast activity, which encourages the production of collagen and elastin.

Derived from highly purified DNA fragments, polynucleotides help improve skin texture, reduce the appearance of fine lines, support tissue regeneration, and enhance overall skin health. They are particularly well suited to delicate areas, including the under-eye region, where traditional volumising treatments may not be appropriate.

Results develop gradually as collagen and elastin production increases, with many patients noticing improvements in skin quality after the first treatment and continued enhancement over the following weeks and months. Polynucleotide treatments are widely used as a non-surgical option for patients seeking natural-looking skin rejuvenation and long-term improvement in skin condition.

Is polynucleotide treatment safe?

Polynucleotide treatment is widely regarded as a safe and well-established option for skin rejuvenation when performed by appropriately qualified medical professionals. The treatment has been used to support skin regeneration, improve skin quality, and address visible signs of ageing across a range of treatment areas.

As with any injectable procedure, a thorough consultation and medical assessment are essential to determine suitability and minimise potential risks. At Dr Nyla Medispa, all polynucleotide treatments are performed within a medically regulated setting under the guidance of Dr Nyla Raja and her experienced medical team.

Who is suitable for polynucleotide treatment?

Polynucleotide treatment may be suitable for individuals looking to improve skin quality, hydration, firmness, and overall skin health without adding volume. It is commonly chosen by patients concerned with fine lines, skin laxity, uneven texture, and age-related changes in the skin.

Polynucleotides are particularly effective in delicate areas such as the under-eye region, where they can help improve skin quality and support tissue regeneration. Suitability will be assessed during your consultation, where a personalised treatment plan will be developed based on your skin concerns and treatment goals.

What are the possible side effects of polynucleotide treatment?

Polynucleotide treatment is generally well tolerated, although, as with any injectable procedure, some temporary side effects can occur. The most common include mild redness, swelling, tenderness, or bruising at the injection sites immediately after treatment.

These effects are typically short-lived and usually resolve within a few days. During your consultation, your practitioner will discuss the potential risks, expected recovery, and appropriate aftercare. For more detailed guidance, read our guide to polynucleotide side effects and aftercare, including what to expect following treatment and when to seek advice.

When will I see results from polynucleotide treatment?

Many patients notice early improvements in skin hydration, texture, and radiance within the first few weeks following treatment. As polynucleotides work by supporting the skin’s natural regenerative processes, results develop gradually rather than immediately.

The full benefits typically become more noticeable over the following 2–3 months as collagen and elastin production increases and skin quality continues to improve. A course of treatments is usually recommended to achieve optimal results. Learn more about polynucleotide results and what to expect.

How long do polynucleotide treatment results last?

The results of polynucleotide treatment can last between 12 and 18 months, although this varies depending on factors such as skin condition, age, lifestyle, and individual response to treatment. As polynucleotides work by supporting the skin’s natural regenerative processes, improvements develop gradually and can continue for several weeks following treatment.

To maintain results, periodic maintenance treatments may be recommended. During your consultation, your practitioner will advise on a personalised treatment plan based on your skin concerns, treatment goals, and long-term skin health.

Where can I have Polynucleotides treatment at Dr Nyla Medispa?

Polynucleotides treatment is available at Dr Nyla Medispa in Mayfair, Alderley Edge, and Crosby. View location-specific treatment information for Polynucleotides in London, Polynucleotides in Cheshire, or Polynucleotides in Liverpool.

How much does polynucleotide treatment cost?

Polynucleotide treatments at Dr Nyla Medispa start from £250.

Our pricing reflects treatment within a doctor-led, medically regulated clinic, with an individualised approach based on your skin concerns, the areas being treated, skin quality, and the treatment plan considered most appropriate for your goals.

Final pricing is provided following a free consultation before treatment, with your practitioner recommending a personalised treatment plan based on your individual needs.

You can also read our guide to polynucleotide treatment costs in the UK for more information about typical prices and the factors that can influence treatment costs.

Begin Your Personalised Treatment Plan With Dr Nyla Medispa

Dr Nyla Raja with the medical aesthetics team at Dr Nyla Medispa in Mayfair, London

Why Choose Dr Nyla Medispa

Dr Nyla Raja is the Founder and Medical Director of Dr Nyla Medispa. With over 20 years of experience in aesthetic medicine, Dr Nyla is recognised for her clinical approach to non-surgical treatments and her commitment to achieving natural-looking results through personalised care.

With clinics in London, Cheshire, and Liverpool, Dr Nyla Medispa provides a carefully selected range of advanced treatments for the face and body. Every treatment is delivered within a medically regulated setting, combining clinical expertise, evidence-based techniques, and a patient-centred approach. Under the guidance of Dr Nyla Raja and her experienced medical team, treatment plans are tailored to individual concerns, with a focus on skin health, facial harmony, and subtle enhancement.

As Featured In

Awards & Recognition

Meet Our Medical Team

Dr Nyla Raja GMC Registered: 6057913
Dr Priyanka Chadha GMC Registered: 7293830
Dr Vadim Corjos GMC Registered: 7822977
Dr Tahera Bhojani-Lynch GMC Registered: 3323786
Dr. S. Dean Rhobaye GMC Registered: 6092830
Dr Paul Cronin GMC Registered: 3056712
Roksana
Roksana Patient Co-Ordinator
Sandra
Sandra Therapist
Emma
Emma General Manager
Dr Nyla Raja GMC Registered: 6057913
Dr Vadim Corjos GMC Registered: 7822977
Dr Tahera Bhojani-Lynch GMC Registered: 3323786
Dr Paul Cronin GMC Registered: 3056712
Dr Kamran Amjed GMC Registered: 7550199
Nurse Antonia Smith Aesthetic Nurse Prescriber
Emma
Emma General Manager
Melissa
Melissa Therapist
Dr Nyla Raja GMC Registered: 6057913
Dr Vadim Corjos GMC Registered: 7822977
Dr Paul Cronin GMC Registered: 3056712
Dr Kamran Amjed GMC Registered: 7550199
Nurse Antonia Smith Aesthetic Nurse Prescriber
Emma
Emma General Manager

What Our Patients Say

Rated Excellent – Based on 500+ Reviews

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Theresa Allen profile picture
Theresa Allen
5 November 2026
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A really lovely experience with Anna very happy with the results, feeling very relaxed
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Lawrence H
5 November 2026
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I’ve always wanted to visit the Dr Nyla clinic living in the SK9 area and I’m truly impressed with the customer service and personal consultation with Dr Nyla herself. I look forward to my treatment in 2027.
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Inayara Kjær profile picture
Inayara Kjær
4 November 2026
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Billie is just amazing! Super experienced, honest and direct. Real results.
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Luke C
13 October 2026
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Amazing Botox with Dr Nyla Last six months highly recommend also had ultherapy and software
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Luke C
13 October 2026
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Amazing Botox with Dr Nyla Last six months highly recommend also had ultherapy and software
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maria thompson profile picture
maria thompson
13 October 2026
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Excellent. Billie was extremely helpful & knowledgable. & was able to answer all my questions & put me at ease
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lynne shackleton
8 October 2026
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Amazing clinic very professional explained everything very clearly would highly recommend
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MsJacam
5 October 2026
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I had a really positive consultation with Dr Nyla at Dr Nyla’s Medi Spa, 32 Dover Street. From the outset, she was warm, professional, open and refreshingly honest. What I appreciated most was that she didn’t sugarcoat anything or try to recommend treatments unnecessarily. She listened carefully to my concerns, gave me realistic advice about what could be achieved, and recommended what she genuinely felt was the best course of treatment for me. I left the consultation feeling informed, reassured and really excited about moving forward. I’m now looking forward to completing my treatment and seeing the final results. So far, a very positive experience and I feel I’m in good hands. I will update this post with my results.
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jackie c profile picture
jackie c
5 October 2026
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Excellent service. Beautiful shop. Consultation very personal with Dr Nyla and gave great advice. Skin care products works really well with my skin.
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Lauren Towers profile picture
Lauren Towers
2 October 2026
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Lovely clinic! Dr Nyla, Anna and Lauren were amazing and made me feel so welcome and well looked after 🥰 thank you and I look forward to my next visit
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Lyndsey Sumner profile picture
Lyndsey Sumner
29 September 2026
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Just had my appointment with Melissa, who discussed my concerns sensitively and helped me consider various treatment options to suit both my budget and skin care concern. Really helpful, wouldn’t hesitate to recommend. Thank you Melissa
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Imogen Drolet profile picture
Imogen Drolet
28 September 2026
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I had a re-evaluation of a thread lift I had done abroad which suddenly acted up by Dr Vadim, who was very reassuring, and was able to explain clearly and concisely what had happened, what to do, and why. Everyone at the clinic was very kind and helpful, and I felt well looked after. Thank you so much!
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Chloe Macleod profile picture
Chloe Macleod
28 September 2026
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Amazing experience at my consultation, felt so welcomed
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Chloe Macleod
28 September 2026
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Amazing experience
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Fellside Construction
17 September 2026
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I went to NYLA clinic and my experience was unbelievable. Anna did my ultra cell treatment which was great and she made me feel very comfortable. Would recommend to anyone x
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Shaz M. profile picture
Shaz M.
13 September 2026
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My wife and I recently visited the clinic—I had a facial, and she received Botox. I can honestly say this is the best clinic I have ever been to.From the moment we walked in, the environment was immaculately clean and incredibly welcoming. The staff were so friendly, guiding us through the entire process and patiently answering every question we had. We were both a bit nervous because of poor experiences at other clinics in the past, but the team completely put us at ease.The treatments themselves were absolutely phenomenal. My facial was one of the best I’ve ever had; I saw a visible improvement in my skin within the first 10 minutes, and the radiant results have lasted. My wife's Botox treatment with Dr. Nyla was exceptional—virtually pain-free, and it has already done wonders for her.Thank you so much to Dr. Nyla and the entire team for turning what we expected to be a nerve-wracking day into an amazing experience. I will be recommending this clinic to absolutely everyone, and we will definitely be returning!
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saral jain profile picture
saral jain
12 September 2026
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Amazing service I look amazing
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saral jain
12 September 2026
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Incredible service would highly recommend. I look amazing
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Rosemary Page profile picture
Rosemary Page
13 August 2026
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Fantastic experience wouldn’t go anywhere else trust the doctors and nurses. They are absolute professionals. Why didn’t I come sooner? it has changed my life
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Nicole Bailey profile picture
Nicole Bailey
6 August 2026
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Everything at Dr Nyla’s Medispa was fabulous, from the team, to the environment, to the treatment itself. Dr Nyla, Anna, Ruby, and Melissa were wonderful and incredibly helpful, I’d recommend this spa to anyone who looking for an honest opinion and reputable provider!

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