Polynucleotide Treatment at Dr Nyla Medispa

Polynucleotides are advanced bio-regenerative injectables designed to improve skin quality, firmness, hydration, and elasticity. Unlike dermal fillers, polynucleotides do not restore volume or alter facial contours. Instead, they work by supporting the skin’s natural repair processes and stimulating fibroblast activity, which encourages the production of collagen and elastin.

Derived from highly purified DNA fragments, polynucleotides help improve skin texture, reduce the appearance of fine lines, support tissue regeneration, and enhance overall skin health. They are particularly well suited to delicate areas, including the under-eye region, where traditional volumising treatments may not be appropriate.

Results develop gradually as collagen and elastin production increases, with many patients noticing improvements in skin quality after the first treatment and continued enhancement over the following weeks and months. Polynucleotide treatments are widely used as a non-surgical option for patients seeking natural-looking skin rejuvenation and long-term improvement in skin condition.

Polynucleotide treatment is widely regarded as a safe and well-established option for skin rejuvenation when performed by appropriately qualified medical professionals. The treatment has been used to support skin regeneration, improve skin quality, and address visible signs of ageing across a range of treatment areas.

As with any injectable procedure, a thorough consultation and medical assessment are essential to determine suitability and minimise potential risks. At Dr Nyla Medispa, all polynucleotide treatments are performed within a medically regulated setting under the guidance of Dr Nyla Raja and her experienced medical team.

Polynucleotide treatment may be suitable for individuals looking to improve skin quality, hydration, firmness, and overall skin health without adding volume. It is commonly chosen by patients concerned with fine lines, skin laxity, uneven texture, and age-related changes in the skin.

Polynucleotides are particularly effective in delicate areas such as the under-eye region, where they can help improve skin quality and support tissue regeneration. Suitability will be assessed during your consultation, where a personalised treatment plan will be developed based on your skin concerns and treatment goals.

Polynucleotide treatment is generally well tolerated, however, as with any injectable procedure, some temporary side effects can occur. The most common include mild redness, swelling, tenderness, or bruising at the injection sites immediately after treatment.

These effects are typically short-lived and usually resolve within a few days. During your consultation, your practitioner will discuss the treatment in detail, including potential risks, expected recovery, and aftercare guidance to help support the best possible outcome.

Many patients notice early improvements in skin hydration, texture, and radiance within the first few weeks following treatment. As polynucleotides work by supporting the skin’s natural regenerative processes, results develop gradually rather than immediately.

The full benefits typically become more noticeable over the following 2–3 months as collagen and elastin production increases and skin quality continues to improve. A course of treatments is usually recommended to achieve optimal results.

The results of polynucleotide treatment can last between 12 and 18 months, although this varies depending on factors such as skin condition, age, lifestyle, and individual response to treatment. As polynucleotides work by supporting the skin’s natural regenerative processes, improvements develop gradually and can continue for several weeks following treatment.

To maintain results, periodic maintenance treatments may be recommended. During your consultation, your practitioner will advise on a personalised treatment plan based on your skin concerns, treatment goals, and long-term skin health.

Polynucleotide treatments at Dr Nyla Medispa start from £250 per session, with a full treatment course available from £1,500. Most patients are advised to undergo a series of treatments spaced several weeks apart to support collagen production, improve skin quality, and achieve optimal results.

Pricing is consistent across our Mayfair, Alderley Edge, and Crosby clinics. During your consultation, your practitioner will assess your concerns and recommend a personalised treatment plan based on the areas being treated and the number of sessions required.