Polynucleotides Treatment
Polynucleotides are a non-surgical bio-regenerative injectable treatment used to improve skin quality, hydration and firmness. Unlike dermal fillers, polynucleotides do not add volume. Instead, they stimulate fibroblast activity and the body’s natural collagen and elastin production, gradually restoring a smoother, healthier and more youthful appearance over a course of treatments.
-
Bio-regenerator injectables that stimulate natural collagen and elastin
-
Targets under-eye hollows, fine lines, skin laxity and texture
-
Aesthetic Awards Finalist 2026, Tatler 2025 Nominated, Elle Beauty 2022
-
Led by Dr Nyla Raja, Medical Director: GMC 6057913
-
From £250 per treatment or £1,500 per course at our Mayfair, Alderley Edge & Crosby clinics
Book a Free Consultation
Expected Results
Tighter, hydrated, and rejuvenated skin
Downtime
Minimal
Longevity
12-18 months
Treatment Time
30 Minutes
Before & After Polynucleotides Treatment
Polynucleotides are particularly effective around the delicate under-eye area. They are a popular treatment for eye area concerns including dark circles, hollowing and crepey skin.
*Disclaimer: Results and patient experience may vary. These are dependent on a number of factors such as age, medical history and lifestyle.
Begin Your Bespoke Aesthetic Journey With Dr Nyla Medispa
What Our Patients Say
Rated Excellent – based on 500+ Reviews
About Polynucleotides Treatment
-
What are polynucleotides?
-
Polynucleotides are chains of nucleotides which are the building blocks of our DNA. Polynucleotides are derived from salmon semen which, when injected into the skin, act as bio-stimulators, triggering our cells to produce new collagen and elastin. These proteins are responsible for skin firmness and elasticity, which naturally deplete as we age. This treatment helps to improve the hydration levels in the skin, stabilise pigmentation and minimise inflammation to enhance the volume and elasticity of the skin for a more youthful appearance.
Polynucleotides represent an advanced, non-surgical anti-ageing treatment renowned for their capacity to regenerate and rejuvenate the skin. Unlike traditional fillers, they are classified as bio-regenerators or bio-stimulators, primarily utilised to enhance skin texture, firmness, and overall quality.
Visible improvements can be observed after the initial treatment session, with the skin appearing more radiant and firm. The full benefits are generally more apparent over the subsequent 2-3 months as the skin continues to produce more collagen and elastin, leading to long-lasting skin rejuvenation.
Polynucleotides are particularly effective in treating delicate areas of the skin that are typically challenging to treat with other injectables, such as the eye area. They are safe and provide a non-invasive alternative to more aggressive cosmetic procedures.
-
How do Polynucleotides Work?
-
Dr Nyla performs her polynucleotide procedures at the Medispa clinics in Alderley Edge in Cheshire, Liverpool and Mayfair in London.
The polynucleotide solution is injected into the areas of concern, such as the face, neck or hands. Once in the skin, these bio-stimulators kickstart the production of fresh collagen and elastin, leading to a gradual improvement in skin quality over subsequent months.
Despite being an injectable treatment, they differ from the likes of dermal fillers or Profhilo because they act as bio-regenerators to encourage the production of collagen for plumper, more hydrated and youthful-looking skin. Over time, they work to improve the firmness and quality of your skin, minimising wrinkles and lines, tightening the skin and hydrating the skin cells for a rejuvenated appearance.
Why Choose Polynucleotides Treatment?
Treatment Process
Enquiry
Consultation
Treatment
Post-treatment Care
FAQs
Your Questions, Answered
Dr Nyla answers the most common questions. If you have a specific question, our team are on hand. Contact us today to get started.
-
Who is the ideal candidate for Polynucleotide treatment?
-
Polynucleotides are suitable for most individuals seeking to improve skin texture, reduce wrinkles and achieve a more youthful appearance. It’s a particularly effective treatment in delicate areas like the eye area, where other injectables may not be recommended.
-
How long do the results last?
-
The results of polynucleotide treatments can last up to 12-18 months, depending on the individual’s skin condition and ageing process. Maintenance treatments may be recommended to sustain the desired results – we can discuss your personalised treatment plan in your consultation, based on your goals and needs.
-
What are the side effects of Polynucleotides?
-
Polynucleotides are typically well-received by most patients but as with any injectable treatment, minor side effects such as redness, swelling or bruising at the injection site may occur. These are typically mild and resolve within a few days.
-
When will I see results?
-
Initial improvements in skin texture and radiance are often visible after the first treatment. However, the full effects of increased collagen and elastin production become more apparent over the subsequent 2-3 months as the skin continues to regenerate.
-
Is Polynucleotide treatment safe?
-
Yes, polynucleotides are considered a safe and effective anti-ageing treatment. As with any injectable procedure, it should only be administered by a qualified and experienced professional in a sterile environment – our team has extensive experience of this treatment for your peace of mind.
Meet the Polynucleotides Treatment Team
Our Medical Team
Clinic Locations
We have three beautiful clinic locations. From our founding Cheshire clinic, to our flagship London Mayfair address in the heart of the capital’s most prestigious district, and our elegant Liverpool location in desirable Crosby, each clinic delivers world-class treatments in luxurious surroundings.
London Mayfair
32 Dover Street
Mayfair
London
W1S 4NE
Our Mayfair clinic is the perfect in London due to it’s proximity to a variety of railway stations and transport links, including Paddington, King’s Cross, St. Pancras, Euston and Marylebone stations.
Cheshire
Castlerock House
Wilmslow Road
Alderley Edge
Cheshire
SK9 7QL
Only 14 miles from central Manchester or 12 miles from the M6. Our Cheshire clinic has free parking and sits nearby luxury shops, bars and cafes.
Liverpool
1 Kenilworth Road
Crosby
Merseyside
Liverpool
L23 3AD
Our Liverpool clinic is based in the highly desirable area of Crosby in the North of the city. There is plenty of free parking.
Related Treatments
Dermal Fillers
ENVY Facial
Exilis Elite Treatment
